Dr María Natalia Gandur Quiroga speaks to ecancer about the updates in renal cancer at ASCO GU 2026.
She says that renal carcinoma (RCC) has entered a new era, shifting from traditional VEGF-driven approaches to a more biologically integrated treatment strategy.
In this expert review, Dr Gandur explores how immunotherapy, HIF-2α inhibition, and emerging biomarkers are reshaping treatment across disease stages, from adjuvant therapy to post-immunotherapy sequencing.
| Belzutifan (bel) plus lenvatinib (lenva) versus cabozantinib (cabo) for advanced renal cell carcinoma (RCC) after anti–PD-(L)1 therapy: Open-label phase 3 LITESPARK-011 study | |
| LITESPARK-022: A phase 3 study of pembrolizumab + belzutifan as adjuvant treatment of clear cell renal cell carcinoma (ccRCC) | |
| Circulating KIM-1 and ctDNA as prognostic markers in oligometastatic clear cell renal cell carcinoma (ccRCC): The K-COMPASS model |