ecancermedicalscience

Case Report

Lymphoepithelioma epidermoid carcinoma of the uterine cervix: surgical management of an isolated case and review of the literature

22 Aug 2025
Tenazoa -Villalobos José Richard, Yan-Quiroz Edgar Fermín, Ordoñez-Chinguel Augusto, Prado-Cucho Sofia Leonor, Villoslada-Terrones Vladimir

Cervical cancer is the gynecological malignancy that ranks third worldwide. It consists histologically of multiple subtypes, such as squamous cell carcinoma, which is the most common (65%), then adenocarcinoma (15%) and other types such as neuroendocrine, adenosquamous and carcinosarcoma tumours, which are less common. According to the World Health Organisation, lymphoepithelioma-type carcinoma has been described as an uncommon subtype and a variant of squamous cell carcinoma of the cervix. Its pathogenesis is related to the presence of the human Epstein-Barr virus and human papillomavirus. We present the case of a woman diagnosed with squamous cell lymphoepithelioma-like carcinoma of the cervix that was comprehensively managed with radical hysterectomy alone, presenting a good response and without recurrence.

Related Articles

Leonardo G Da Fonseca, Duilio Reis da Rocha Filho, Aline Lopes Chagas, Alexandre Jacome, Leila Moreira Beltrao Pereira, Rogerio Alves, Mario Reis Alvares-da-Silva, Mauro Donadio, Ana Paula Victorino, Federico Piñero, Cassia Guedes Leal
Olufemi Abiola Oyedeji, Ayoola Moses Bakare, Nosimot Omolola Davies, Olusola Festus Olowoselu, Ann Abiola Ogbenna
Zakayo Ernesti, Emanuel Lugina, Chacha J Mwita, Felister Tupa, Herriethsiah S Noah, John R Ngowi, Charles Wood, Julius Mwaiselage, Salum J Lidenge
Neha Singh, Sujata Agrawal, Zachariah Chowdhury, Shashikant Patne, Ipsita Dhal, Paramita Paul, Sadaf Haiyat, Akhil Kapoor, Anuj Gupta, Bal Krishna Mishra, Mayank Tripathi, Bipinesh Sansar
Edwin Saji, Jason Jacob, Udaya Kumar Damodaran, Sabah Kulsum, Sharanya Tripathi, Akshat Saxena, Panah Parab, Utkarsh Dayal, Priyal Dilip Mehta, Aju Mathew