ecancermedicalscience

Case Report

Eribulin-induced radiation recall dermatitis: a case report and brief review of the literature

23 Jan 2020
William T Tran, Carolina Ibáñez, Mauricio P Pinto, Cesar Sánchez, Gregory J Czarnota, Tomás Merino

Background: Radiation recall (RR) is a fairly uncommon and unpredictable phenomenon caused by an acute inflammatory reaction in a previously irradiated area. Several antineoplastic drugs have been previously associated with RR reactions including anthracyclines and taxanes like docetaxel, paclitaxel or antimetabolites.

Case presentation: Here we report for the first time a case of a recall reaction to Eribulin mesylate, a novel chemotherapeutic compound that affects microtubule polymerisation, approved for the treatment of metastatic or locally advanced breast cancers (BCs). We present the case of a 61-year-old female BC patient originally diagnosed with bilateral BC with metastatic disease that went through several lines of chemotherapy and radiation therapy (RT); RR reaction was observed following Eribulin treatment and sequential palliative RT.

Conclusion: This case report raises awareness about these fairly rare phenomena when prescribing Eribulin, or any new chemotherapeutic after RT to prevent and treat as early as possible to avoid further patient complications.

Article metrics: 187 views
144
43

Related Articles

Muhammad Shahid Iqbal, Joseph Carlow, Fiona McDonald, Philip Atherton, Helen Turnbull, Sandeep Singhal, Timothy Simmons, Paula Mulvenna, Josef Kovarik, Rhona McMenemin, Jill Gardiner, Alastair Greystoke
Monique Binotto, Tomás Reinert, Gustavo Werutsky, Facundo Zaffaroni, Gilberto Schwartsmann
Cristóbal Maiz, Fernando Silva, Francisco Domínguez, Héctor Galindo, Mauricio Camus, Augusto León, David Oddó, Alejandra Villarroel, Dravna Razmilic, María Elena Navarro, Lidia Medina, Tomás Merino, Eugenio Vines, José Peña, Daniela Maldonado, Mauricio P Pinto, Francisco Acevedo, Cesar Sánchez
Catarina Marchon da Silva, Denis Shimba, Denise Oishi, Allyne Cagnacci, Ana Carolina Ribeiro Chaves de Gouvea, Felipe Ades