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Dr Jana Fox speaks to ecancer about intraoperative radiation therapy for early-stage breast cancer.
IORT is used for women with early-stage breast cancer, especially those with low to intermediate-grade ER-positive DCIS or small invasive ductal carcinomas.
Dr Fox says that at her institute, a multidisciplinary team makes treatment decisions, and surgeons refer patients to radiation oncology post-lumpectomy.
IORT uses low-energy X-rays and is suitable for patients unable to tolerate external beam radiation.
It shows a local recurrence rate under 2% over three years and is being studied as an alternative treatment.
The use of IORT at Montefiore Medical Center
Breast conserving surgery and IORT can manage locally recurrent breast cancer
Rationale for routine use of IORT for early breast cancer and data for specific indications
Breast and emerging indications for IORT
The advantages of IORT for early breast cancer treatment
The pros and cons of breast IORT and ultra hypofractionation (FR)
Rationale for routine use of IORT for early breast cancer and data for specific indications
Single-dose IORT during lumpectomy for breast cancer an innovative patient-centred treatment
Global adoption of single-shot targeted IORT for breast cancer
