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ReDO_DB: the repurposing drugs in oncology database

6 Dec 2018
Pan Pantziarka, Ciska Verbaanderd, Vidula Sukhatme, Rica Capistrano, Sergio Crispino, Bishal Gyawali, Ilse Rooman, An MT Van Nuffel, Lydie Meheus, Vikas P Sukhatme, Gauthier Bouche

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

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