ecancermedicalscience

Research

ReDO_DB: the repurposing drugs in oncology database

6 Dec 2018
Pan Pantziarka, Ciska Verbaanderd, Vidula Sukhatme, Rica Capistrano, Sergio Crispino, Bishal Gyawali, Ilse Rooman, An MT Van Nuffel, Lydie Meheus, Vikas P Sukhatme, Gauthier Bouche

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

Related Articles

Jade Tso, Mustafa Al-Qaraghli, Susana Galeas, Mustafa Faleh Abidalhassan, Cameron E Gaskill
Samuel Santiago Parra Giraldo, Rut Amparo Vergara López, Haydee De La Hoz-Herazo, Enrique Carlos Ruiz Pla, Brayan Bayona-Pacheco, Juan Jose Espitia De La Hoz
Soumitra Shankar Datta, Heena Sheth, Sharmili Ghosh, Srijan Das, Jigeesha Ghosh, Dishari Choudhury, Arnab Mukherjee, Soumita Ghose, Romy Biswas, Maria Castrillo Gil, Carlos Andres Gamboa Alfaro, Mary Guevara, Danny Burke, Sujit Sarkhel, Jai Ranjan Ram
Diego Rodrigues Mendonça e Silva, Max Moura de Oliveira, Gisele Aparecida Fernandes, Maria Paula Curado