ecancermedicalscience

Research

ReDO_DB: the repurposing drugs in oncology database

6 Dec 2018
Pan Pantziarka, Ciska Verbaanderd, Vidula Sukhatme, Rica Capistrano, Sergio Crispino, Bishal Gyawali, Ilse Rooman, An MT Van Nuffel, Lydie Meheus, Vikas P Sukhatme, Gauthier Bouche

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

Related Articles

Hafssa El Hilali, Nassiba Bahra, Sanae Guennouni, Chaymae Chbihi, Samia El Hakym, Diango Keita, Sara Nejjari, Abir Oufrid, Oumaima Siyouri, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim, Touria Bouhafa, Nawfel Mellas, Samira El Fakir, Samia Arifi
Bincy Mathew, Nitin Yashas Murthy, Amit Rauthan, Poonam Patil, Devesh Ballal, Shabber S Zaveri, Guddahatty Nanjappa Hemanth, Ananthakrishnan Nidheesh, Nidudi Javaregowda Harshitha
Alfred Jatho, Sheba Nakacubo Gitta, Vincent K Kalungi, Ronald Opito, Samuel Okello, Robinah Komuhendo, James Kafeero, Noleb Mugisha