The SUMO conjugating enzyme UBC9 as a biomarker for cervical HPV infections

29 Apr 2015

Domenico Mattoscio, Chiara Casadio, Marzia Fumagalli, Mario Sideri, Susanna Chiocca

Human papillomaviruses (HPVs) infect stratified epithelium and are the causative agents of cervical cancer, the second most common cause of cancer-related death in women. A critical aspect that still persists in the HPV field is the selection of very sensitive and specific HPV diagnostic assays. Here, we provide evidence that the crucial small ubiquitin-like modifier (SUMO) E2-conjugating enzyme Ubc9 is strongly upregulated in cervical lesions. Ubc9 detection could thus be used in diagnosing and/or monitoring the progression of an HPV oncogenic infection.

2091-brachytherapy-reirradiation-for-local-recurrences-of-gynaecological-cancers-two-clinical-cases-literature-review-and-oar-constraints

Review: Brachytherapy reirradiation for local recurrences of gynaecological cancers: two clinical cases, literature review and OAR constraints

Javier Faundez, Carlos Schananier, Cynthia Villegas, Javier Retamales

12 Mar 2026

https://doi.org/10.3332/ecancer.2026.2091

Abstract | Full Article | PDF

Research: Cancer profile among medical evacuees from São Tomé and Príncipe: a descriptive study (2019–2025)

Liudmila Castelo David, Teresa Mota Garcia, Isaulina Barreto, Esperança Carvalho, Laurinda Barreto, Clara Aleydis, Laurinda Coelho, Lúcio Lara Santos

12 Mar 2026

https://doi.org/10.3332/ecancer.2026.2093

Abstract | Full Article | PDF

2085-symptom-palliation-with-quadshot-regimen-for-advanced-cervical-cancer-patients-in-tikur-anbessa-specialised-hospital-a-prospective-cohort-study

Research: Symptom palliation with QUADSHOT regimen for advanced cervical cancer patients in Tikur Anbessa Specialised Hospital: a prospective cohort study

Tsion Zebdiwos Chema, Edom Seife Woldetsadik, Girum Tessema Zingeta, Hawi Furgassa Bedada, Mohammed Ibrahim Adem, Jilcha Diribi Feyisa, Winini Belay, Mushonga Melinda, K S Han Kathy, Rebecca Wong, Munir Awol, Bargude Balta

9 Mar 2026

https://doi.org/10.3332/ecancer.2026.2085

Abstract | Full Article | PDF

2081-social-and-clinical-factors-associated-with-non-adherence-to-radiotherapy-with-curative-intent-in-a-cancer-centre-in-peru

Research: Social and clinical factors associated with non-adherence to radiotherapy with curative intent in a cancer centre in Peru

Robles Díaz, José Fernando, Flores Romaní, Lucero Silvana

24 Feb 2026

https://doi.org/10.3332/ecancer.2026.2081

Abstract | Full Article | PDF

2071-the-global-cancer-crisis-a-review-of-growing-burden-deepening-inequality-and-initiatives-for-prevention-and-early-detection

Review: The global cancer crisis: a review of growing burden, deepening inequality and initiatives for prevention and early detection

Charles M Balch, Ning Liao, Dennis S C Lam, Jeffrey N Weitzel, Rui-Hua Xu, Gerhardt Attard, Paul A Bunn, Alexander M M Eggermont, Jie He, Yuko Kitagawa, Soon Thye Lim, Eduardo Cazap, Bernard Esquivel, Xianqun Fan, Louis W C Chow, Edward S F Liu, Hector Martinez Said, John E Niederhuber, Isabel T Rubio, Ashraf Saad Zaghloul, Oscar G Arrieta, Riccardo A Audisio, Geerard L Beets, Felipe J F Coimbra, Jorge E Gallardo, Judy E Garber, Alessandro Gronchi, Volker Heinemann, Allison W Kurian, Miriam Mutebi, Masaki Mori, Funmi I Olopade, Piotr Rutkowski, Mansoor Saleh, William M Sanchez, Raymond Sawaya, John F Thompson, Gerald Tumusiime, Carlos S Vallejos, David C Whiteman, YiLong Wu, King-David T Yawe, Nayef Awad Al Zahrani, Odysseas Zoras, Banu K Arun, Carol J Fabian, Jeffrey E Gershenwald, William J Gradishar, Jin He, V Suzanne Kimberg, Ronald M K Lam, Victor H F Lee, Domenica Lorusso, Tony S K Mok, N D Perrier, Hope S Rugo, Cornelia Ulrich, Chandrakanth Are, J Vignat, I Soerjomataram

3 Feb 2026

https://doi.org/10.3332/ecancer.2026.2071

Abstract | Full Article | PDF