ecancermedicalscience

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

8 Jan 2015
Shripad Banavali, Eddy Pasquier, Nicolas André

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Related Articles

Saira Saleem, Iffat Aleem, Aribah Atiq, Sahrish Tariq, Amna Babar, Muhammad Abu Bakar, Madiha Syed, Maheen Maruf, Mohammad Tariq Mahmood, Muhammad Zeshan, Muhammad Tahseen, Raza Hussain, Asif Loya, Chris Sutton
Arvind Kumar, Kunal Oswal, Ravikant Singh, Neha Kharodia, Akash Pradhan, Lakshman Sethuraman, Ramachandran Venkataramanan, Arnie Purushotham
Duilio R Rocha-Filho, Renata D’Alpino Peixoto, Rui F Weschenfelder, Juliana F M Rego, Rachel Riechelmann, Anelisa K Coutinho, Gustavo S Fernandes, Alexandre A Jacome, Aline C Andrade, Andre M Murad, Celso AL Mello, Diego S C G Miguel, Diogo B D Gomes, Douglas J Racy, Eduardo D Moraes, Eduardo H Akaishi, Elisangela S Carvalho, Evandro S Mello, Fauze Maluf Filho, Felipe J S Coimbra, Fernanda C Capareli, Fernando F Arruda, Fernando M A C Vieira, Flavio R Takeda, Guilherme C C Cotti, Guilherme L S Pereira, Gustavo A Paulo, Héber S C Ribeiro, Laercio G Lourenco, Marcela Crosara, Marcelo G Toneto, Marcos B Oliveira, Maria de Lourdes Oliveira, Maria Dirlei Begnami, Nora M Forones, Osmar Yagi, Patricia Ashton-Prolla, Patricia B Aguillar, Paulo C G Amaral, Paulo M Hoff, Raphael L C Araujo, Raphael P Di Paula Filho, Rene C Gansl, Roberto A Gil, Tulio E F Pfiffer, Tulio Souza, Ulysses Ribeiro Jr, Victo Hugo F Jesus, Wilson L Costa Jr, Gabriel Prolla
Zineb Benbrahim, Layth Mula-Hussain, Humaid O Al-Shamsi, Nagi El Saghir, Mushabbab Al Asiri, Bassim Al Bahrani, Muath Al Nassar, Adda Bounedjar, Zahera Fahed, Sami Khatib, Ola Khorshid, Soumaya Labidi, Nawfel Mellas, Amani Saleh, Abdulrahman Jazieh
Adedayo O Joseph, Ya-Huei Li, Omolola Salako, Suhail Doi, Onyinye D Balogun, Opeyemi M Awofeso, Fatimah Abdulkareem, Adedayo A Onitilo