ecancermedicalscience

Case Report

Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation

5 Aug 2013
Savita Chaudhary, Cherry Bansal, Upasna Ranga, KK Singh

Mycosis fungoides (MF) is the most common variant of primary cutaneous T-cell lymphoma (CTCL). It is generally associated with an indolent clinical course and characterised by well-defined clinicopathological features. Although rare, CTCLs constitute 65% of all cutaneous lymphoid malignancies, of which 50% are patients with MF. The erythrodermic variants of MF, a malignancy of mature, skin homing and clonal T lymphocytes, usually present in mid to late adulthood. Association with hypereosinophilia is important in prognosis. We report a case of erythrodermic MF with hypereosinophilic syndrome in a 22-year-old female presenting with gradually progressive intractable erythroderma with intensely pruritic multiple papules, plaques, and nodules involving more than 90% of body surface area. Diagnosis was confirmed by histopathological examination and immunophenotyping from multiple skin biopsies.

Related Articles

Sambuddha Das, Aditi Bhowmik, Abhinandan Bhattacharjee, Biswadeep Choudhury, Momota Naiding, Bishal Dhar, Agniv Kr Laskar, Jayeeta Pandit, Sankar Kumar Ghosh, Yashmin Choudhury
Zoya Peelay, Deevyashali Parekh, Vijay M Patil, Vanita Noronha, Nandini Menon, Kumar Prabhash
Lucky E Tietie, Kehinde S Okunade, Adaiah P Soibl-Harry, Sarah O John-Olabode, Rose I Anorlu
Annie Kanchan Baa, Sameer Rastogi, Sanal Fernandes, Shakti Shrivastava, Rajni Yadav, Adarsh Barwad, Shamim A Shamim, Nihar Ranjan Dash