Subcutaneous versus intravenous administration of Trastuzumab: a minimization cost analysis with real world data from a reference cancer centre in Peru

31 May 2024
Iris Otoya, Natalia Valdiviezo, Katia Roque, Zaida Morante, Tatiana Vidaurre, Silvia P. Neciosup, Mónica J. Calderón, Henry L. Gomez

Breast cancer (BC) is a global concern, with Peru experiencing a high incidence and mortality. Trastuzumab, a crucial treatment for human epidermal growth factor receptor 2-positive BC, is administered intravenously or subcutaneously (SC). This study evaluates the costs associated with both methods at Peru's Instituto Nacional de Enfermedades Neoplásicas. Real data indicate that SC administration reduces treatment costs by approximately S/15,049.09. Cross-continental comparisons highlight a global trend favouring SC administration for efficiency and cost-effectiveness. The analysis provides insights for informed decision-making in resource-constrained healthcare settings like Peru, emphasising the need to consider local contexts in optimising oncology care.

Related Articles

Mohammad Saad Salim Naviwala, Mirza Rameez Samar, Daania Shoaib, Fizza Akbar, Romana Idrees, Yasmin Abdul Rashid
Isabel Saffie-Vega, Sergio Muñoz-Navarro, Macarena Manríquez-Mimica, Jorge Sapunar-Zenteno
Raúl Sandoval-Ato, Patricia Coral-Gonzales, Sebastian Coronel-Arias, Luisa Espinoza-Mantilla, Grace Terrones-Chaparro, Victor Serna-Alarcón
Francisco E Villanueva, Natalia S Jara, Valentina Darlic