ecancermedicalscience

Research

Is there a role for 'modified VAD' in the treatment of multiple myeloma?

4 Jun 2009
A Agazzi, S Sammassimo, D Laszlo, SJ Liptrott, R Cascio, A Alietti, C Rabascio, P Mancuso, G Pruneri, G Martinelli

VAD, (Vincristine, Doxorubicin and Dexamethasone) was initially proposed as a salvage therapy for myeloma patients in whom prior alkylating agent therapy failed, although in recent years VAD has been surpassed by novel combination therapies with new biological agents such as thalidomide (and its derivative, lenalidomide) and bortezomib. After the excellent results obtained by the novel agents, VAD can no longer be proposed in preparation to autologous transplantation, although there are still indications that VAD remains useful and clinically relevant in the initial treatment of symptomatic multiple myeloma.

Related Articles

Glenn M Afungchwi, Elianeth Kiteni, Mariam Ndagire, Biemba Maliti, Rachael Kunkel, Julia M Challinor, Rachel Hollis
Raunaq Puri, Madhup Rastogi, Ajeet Kumar Gandhi, Rohini Khurana, Rahat Hadi, Shantanu Sapru, Anshuman Pandey, Akash Agarwal, Anoop Kumar Srivastava, Surendra Prasad Mishra, Farhana Khatoon, Avinav Bharati, Vachaspati Kumar Mishra, Akanksha Manral, Prasoon Mishra
Annie Kanchan Baa, Atul Sharma, Suman Bhaskar, Ahitagni Biswas, Alok Thakar, Rajeev Kumar, Sreeja Jayant, Gourishankar Aland, Alain D’Souza, Vikas Jadhav, Atul Bharde, Jayant Khandare, Raja Pramanik
Siraji Obayo, Yusuf Mulumba, Cheryl L Thompson, Michael K Gibson, Matthew M Cooney, Jackson Orem
Uchenna Simon Ezenkwa, Gabriel Olabiyi Ogun, Mbwas Isaac Mashor, Olufemi John Ogunbiyi