ecancermedicalscience

Research

A review of breast cancer pathology reports in Nigeria

23 Feb 2021
Adedayo O Joseph, Ya-Huei Li, Omolola Salako, Suhail Doi, Onyinye D Balogun, Opeyemi M Awofeso, Fatimah Abdulkareem, Adedayo A Onitilo

Background: Diagnosis and treatment of cancer rely heavily on imaging, histopathology and molecular information. Incomplete or missing tumour information can hinder the delivery of high-quality care in oncology practice, especially in resource-limited countries. To evaluate the completeness of histopathology reporting in a real-world setting and identify areas for future cancer care delivery research efforts, we retrospectively analysed reports from patients diagnosed with breast cancer who received care at a high-volume oncology department at a hospital in Lagos, Nigeria.

Methods: Demographic, institutional and histopathology characteristics were retrospectively obtained from 1,001 patient records from 2007 to 2016. Completeness was defined as reporting five tumour features (tumour histology, tumour grade, laterality, oestrogen receptor (ER) or progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2)) for biopsy specimens and seven tumour features (tumour size, tumour histology, tumour grade, laterality, ER/PR, HER2 and lymph node involvement) for surgical specimens.

Results: The mean age of patients was 48.6 ± 11.7 years with a predominantly female population (99.3%). A majority of pathologic reports were produced after 2011, and two-thirds of the reports originated from centres or labs within Lagos, Nigeria (67.7%). Most reports documented primary site (98.0%) and specimen type (85.0%) while other characteristics were less often recorded. This led to substantial variation in reporting between biopsy (13.4%) and surgical (6.1%) specimens for an overall low pathology report completeness <10%.

Conclusion: The majority of patient records analysed lacked complete documentation of breast cancer histopathological characteristics commonly used in oncology practice. Our study highlights a need to identify and address the contributing factors for incomplete histopathological reporting in Nigeria and will guide future clinical programmatic developments.

Related Articles

Sanjit Kumar Agrawal, Vishal Kewlani, Noopur Priya, Abhishek Sharma, Joydeep Ghosh, Sanjoy Chatterjee, Rosina Ahmed
Amit Joshi, Vijay Maruti Patil, Vanita Noronha, Atanu Bhattacharjee, Nandini Menon, Amit Kumar, Parmanand Jain, Sadaf Mukadam, Avadhoot Shrinivas, Anjali Punia, Anuja Abhyankar, Amit Agarwal, Satvik Khaddar, Anu Rajpurohit, Kanteti Aditya Pavan Kumar, Rahul Ravind, Kishore Das, Vikas Talreja, Sachin Dhumal, Kumar Prabhash
Jemma Arakelyan, Alisa Movsisyan, Lilit Sargsyan, Armine Chopikyan, Diana Andreasyan, Arevik Torosyan, Ruzanna Papyan, Hovhannes Vardevanyan, Samvel Bardakhchyan, Artashes Tadevosyan, Gevorg Tamamyan, Armen Tananyan, Samvel Danielyan, Dickran Kazandjian
Deepthi Valiyaveettil, Swapna Jilla, Jonnalagadda Mohan Krishna, Raja Kollu, Chandrasekhar Patil, Ranadheer Gupta
Hagar Elghazawy, Joaira Bakkach, Thanaa Helal, Ahmed M Aref, Mohamed Kelany, Lamiaa E Abdallah, Fatma S Abdelbakey, Dalia Ali, Doaa Z Ali, Mai O Ahmed, Amer Ali Abd El-Hafeez, Pradipta Ghosh, Mohamed O Alorabi
Vilma Adriana Tripodoro, Victoria Llanos, María Laura Daud, Pilar Muñoz, Eden Del Mar, Romina Tranier, Sol Sandjian, Silvina De Lellis, Juan Manuel Días, Alvaro Saurí, Gustavo Gabriel De Simone, Xavier Gómez-Batiste