Gene expression test guided therapy in ER+/HER2- early breast cancer allows safe chemotherapy omission

Tarlatamab in SCLC shows consistent effect and low immune toxicity across age groups

Weight loss intervention improves quality of life in breast cancer survivors

Adjuvant avelumab reduces relapse risk in stage III Merkel cell carcinoma

MCED blood test trial fails primary end point, but screening cut number of cancers found at stage IV

Fedratinib improves spleen and symptom responses with promising survival outcomes in MDS/MPN and CNL

177Lu-rosopatamab plus standard of care shows manageable safety and favourable tumour targeting in mCRPC

GLP-1 use linked to improved survival in patients with cancer

Darovasertib plus crizotinib improves outcomes in HLA-A2–negative metastatic uveal melanoma

Olaparib plus pembrolizumab improves response but not PFS in BRCA-mutant pancreatic cancer

Early-onset gastrointestinal cancers show more advanced disease and wider racial survival gaps

Xaluritamig plus abiraterone shows promising anti-tumour activity with manageable safety in chemotherapy-naïve mCRPC