ecancermedicalscience

Research

The mortality-incidence ratio as an indicator of five-year cancer survival in metropolitan Lima

18 Jan 2018
Karoline Stenning-Persivale, Mara Jose Savitzky Franco, Alejandra Cordero-Morales, José Cruzado-Burga, Ebert Poquioma, Edgar Díaz Nava, Edouardo Payet

Introduction: The Mortality–Incidence Ratio complement [1 – MIR] is an indicator validated in various populations to estimate five-year cancer survival, but its validity remains unreported in Peru. This study aims to determine if the MIR correlates directly with five-year survival in patients diagnosed with the ten most common types of cancer in metropolitan Lima.

Materials and methods: The Metropolitan Lima Cancer Registry (RCLM in Spanish) for 2004–2005 was used to determine the number of new cases and the number of deaths of the following cancers: breast, stomach, prostate, thyroid, lung, colon, cervical, and liver cancers, as well as non-Hodgkin’s lymphoma and leukaemia. To determine the five-year survival, the five-year vital status of cases recorded was verified in the National Registry of Identification and Civil Status (RENIEC in Spanish). A linear regression model was used to assess the correlation between [1 – MIR] and total observed five-year survival for the selected cancers.

Results: Observed and estimated five-year survival determined by [1 – MIR] for each neoplasia were thyroid (66.7%, 86.7%), breast (69.6%; 68%), prostate (64.3%, 63.8%) and cervical (50.1%, 58.5%), respectively. Pearson’s r coefficient for the correlation between [MIR – 1] and observed survival was = 0.9839. Using the coefficient of determination, it was found that [1 – MIR] (X) captures the 96.82% of observed survival (Y).

Conclusion: The Mortality–Incidence Ratio complement [1 – MIR] is an appropriate tool for approximating observed five-year survival for the ten types of cancers studied. This study demonstrates the validity of this model for predicting five-year survival in cancer patients in metropolitan Lima.

Related Articles

Adewale Isaiah Oyewole, Funmilola Olanike Wuraola, Amir H Sohail, Titilope Ogunniyi, Chinyere Nwankwo, Zainab Oyindamola Adegbite, Dorcas Olaide Ebekue, Clement D Awe, Elizabeth N Christian, Kristina Diaz, Oluwasegun Afolaranmi, Clara N Lambert, Dan Sherman, George Gutierrez, Chinenye Iwuji, Juliet S Lumati
Ally H Mwanga, Jeanine Justiniano, Eric M Mbuguje, Balowa Musa, Deogratius B Mwanakulya, Andrew Swallow, Edith Kimambo, Eva Uiso, Swaleh Pazi, Latifa Rajab, Nashivai E Kivuyo, Larry Akoko, Azza Naif, Advera Ngaiza, Sara Nyagabona, Jerry Ndumbalo, Amos R Mwakigonja, Jim E Littlejohn, Seif Wibonela, Cameron E Gaskill
Rodrigo Lastra, Patricia Iranzo, Javier-David Benítez-Fuentes, Ana Callejo, Mara Cruellas, Jacobo Gómez Ulla, Isabel Pimentel, José Luis Pérez-Gracia, Marta Ramos, Francisco Gil Moncayo, María Álvarez Alejandro, Marta Gascón, Sergio Martínez Recio, Pilar Rivero, Jorge Bartolomé, Antonio David Lázaro Sánchez, David Fernández Garay, Alicia de Luna Aguilar, Isabel Lorenzo Lorenzo, Joan Brunet, Noemi Reguart, Dario Trapani
Kamlesh M Bhojwani, Ahmed Raheem, Urooba Tariq Khan, Fahad Javid, Daniyal Tanweer, Nawal Rehmani, Nadeem Ullah Khan, Saqib Raza Khan
Juzzel Ian Zerrudo, Patrick Vincent Aquino, Christian Joseph Tagal, Ma Erica Valdeabella, Christian Norwiz Buenviaje