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Circulating microRNAs: next-generation biomarkers for early lung cancer detection

6 Mar 2012
F Bianchi, F Nicassio, G Veronesi, PP Di Fiore

Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the detection of circulating microRNAs, which can identify at-risk individuals with asymptomatic early stage nonsmall cell lung carcinomas with 80% accuracy.

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