ecancermedicalscience

Review

Might salicylate exert benefits against childhood cancer?

19 Jan 2010
G Morgan, JI Johnsen

Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostaglandins, which have been shown to stimulate the growth of cancer cells. Secondly, salicylate inhibits the growth of cancer cells in pre-clinical models. Thirdly, salicylate is a natural component of fruits and vegetables so it is consumed within the diet. Further research, of which some possibilities are identified, is recommended.

Related Articles

Trishna Chaudhuri, Devi Nandakumar, Soumitra Shankar Datta, Zakir Husain, Reghu K Sukumaran, Inder Sekhar Yadav, Sekhar Krishnan, Samiran Panda
Arnab Mukherjee, Chitralekha Bhowmick, Shreshta Chattopadhyay, Mohamed Abdul Kathar, Moitri Bhattacharyya, Shazia Nasreen, Prateek Jain, Pattatheyil Arun, Soumitra Shankar Datta
Marina Vieira Rodrigues de Queiroz, Ana Carolina Tardin Rodrigues de Medeiros, Sarah Pires Toledo, Karina Demoner de Abreu Sarmenghi, Vitor Fiorin de Vasconcellos
Rahat Ul-Ain, Mahwish Faizan, Saadia Anwar, Shazia Riaz, Alia Ahmad, Huma Zafar, Wasila Shamim