ecancermedicalscience

Research

Cost-effectiveness of breast, lung, colon, prostate and cervical cancer outcomes in Brazil: a worldwide comparison

7 Jun 2021
Rodrigo Pellegrini, Tomás Reinert, Carlos Henrique Barrios

Introduction: Cancer is the second leading cause of death in the world, and it is expected to be the main cause by the year 2030. Current trends of higher incidence and the introduction of new treatments lead to the challenge of treating more people with increasing costs per capita. In Brazil, current and future challenges are even more significant because of the limited resources destined for healthcare.

Methods: We propose a methodology to compare cost-effectiveness performance with a regression of cancer lethality against the resources available for different nations, using the gross domestic product and the mortality-to-incidence ratio. Our objective is to evaluate and compare outcomes observed in Brazil.

Results: According to our methodology, Brazil is performing well in breast and prostate cancer (observed lethality 9% and 15% lower than expected, respectively). It performs close to expected in colon (0.8% higher) and cervix (2% higher). However, lung cancer had a higher lethality than expected (6.5% higher). We also found that breast, prostate and cervical cancers are the primary sites more related to income. Lung cancer had the weakest relationship with resources.

Conclusion: Brazil has different cost-effectiveness results in the management of cancer depending on the primary site. Also, national income has a significant and heterogeneous effect on the lethality of different tumour types. This economic analysis is important for low- to middle-income countries seeking to evaluate cancer outcomes in limited-resource settings.

Related Articles

Yasmim Portela Machado de Aguiar, Adjanny Estela Santos de Souza, Christian Diniz Lima e Silva, Sândrea Ozane do Carmo Queiroz
Lucrecia Aline Cabral Formigosa, Luciana Ferreira dos Santos, Joana Dulce Cabral Formigosa, Denise da Silva Pinto, Danielle Saraiva Tuma dos Reis, Marcos Valério Santos da Silva
Vijay Patil, Vanita Noronha, Dilip Harindran Vallathol, Nandini Menon, Abhishek Mahajan, Amit Janu, Nilendu Parandare, Kumar Prabhash
Yumna Ahmed, Agha Muhammad Hammad Khan, Fatima Shaukat, Rabia Tahseen, Maria Tariq, Bilal Mazhar, Sehrish Abrar, Nasir Ali