ecancermedicalscience

Case Report

Tamoxifen exposure in pregnancy after synchronous breast and thyroid cancer

15 Oct 2020
Abeid M Athman Omar, Amany Abdel-Bary, Rasha O Elsaka

Thyroid and breast cancer are the most common cancers among young women, which are either synchronous or metachronous, but the association is yet to be elucidated. With the improvement of diagnosis and treatment, there is an increase in breast and thyroid cancer survivors. Hence, attention is shifting towards survivorship. Here, we report the case of a young lady diagnosed with synchronous thyroid and breast cancer who unexpectedly became pregnant during tamoxifen treatment. After a multidisciplinary discussion, endocrine therapy was interrupted and she delivered a healthy baby at term. In conclusion, oncologists should be aware of breast and thyroid cancer co-occurrence and examinations should be conducted together in diagnosis and follow-up. Also, pregnancy is feasible and can be considered after synchronous breast and thyroid cancer diagnosis. Physicians need to emphasise the use of barrier contraceptives to patients undergoing endocrine therapy. However, the optimum timing for pregnancy after breast cancer and the safety of endocrine therapy interruption in hormonal-positive patients should be discussed and managed by a multidisciplinary team.

Related Articles

Ramachandran Venkataramanan, Akash Pradhan, Abhishek Kumar, Mohannad Alajlani, Theodorus N Arvanitis
Berthe Sabine Esson Mapoko, Andreas Frambo, Yauba Saidu, Esther Dina Bell Mbassi, Etienne Atenguena, Kareen Azemafac, Emily Kobayashi, Lionel Tabola, Glenda Nkeng, Anne Sango, Anne Marthe Maison, Sidonie Ananga Noa, Ambroise Ntama, Ruth Rosine Meka’h Mapenya, Rachel Tayou, Francine Kouya, Glenn Mbah, Pelagie Douanla, Celestin Fonkwa, Martin Essomba Biwole, Zacharie Sando, Albert Mouelle Sone, Paul Ndom
Sonali Bagal, Atul Budukh, Jarnail Singh Thakur, Tapas Dora, Burhanuddin Qayyumi, Divya Khanna, Dolorosa Fernandes, Priyal Chakravarti, Ravikant Singh, Suvarna Patil, Rajesh Dikshit, Pankaj Chaturvedi
Lucas Avondet, Roque Adan, Barbara M Berenstein, Gonzalo Zeballos, Nicole Brasquet, Ángeles Da Silva, Candela Bazan, Gisela Coliva, Ximena Garcia