ecancermedicalscience

Visions

The interplay between NCAM and FGFR signalling underlies ovarian cancer progression

20 Oct 2011
U Cavallaro, N Colombo

Epithelial ovarian carcinoma (EOC) is an aggressive neoplasm, which has often disseminated to peritoneal cavity at the time of diagnosis. In order to better understand the molecular mechanisms behind EOC progression, we investigated the expression and functional role of neural cell adhesion molecule (NCAM) in this tumour type.