T-cell engagers in mAPMR/mCRPC prostate cancer

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Published: 25 Oct 2026
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Dr Dominik Berthold - Centre Hospitalier Universitaire Vaudois—CHUV, Lausanne, Switzerland

Dr Dominik Berthold updates ecancer at ESMO 2026 about a new area of potential treatment using bispecific T-cell engagers.

This emerging class of targeted immunotherapies is being investigated for advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC, also known as metastatic androgen pathway modulation-resistant prostate cancer) and neuroendocrine prostate cancer (NEPC).

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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