Perioperative pembrolizumab fails to significantly improve event-free survival in muscle-invasive bladder cancer
Dr Dominik Berthold updates ecancer at ESMO 2026 about a new area of potential treatment using bispecific T-cell engagers.
This emerging class of targeted immunotherapies is being investigated for advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC, also known as metastatic androgen pathway modulation-resistant prostate cancer) and neuroendocrine prostate cancer (NEPC).
Perioperative pembrolizumab fails to significantly improve event-free survival in muscle-invasive bladder cancer
Novel therapies in mCRPC: Tarlatamab targeting DLL3 shows early activity in neuroendocrine mCRPC
Adjuvant avelumab reduces relapse risk in stage III Merkel cell carcinoma
Mezigdomide plus carfilzomib and dexamethasone delays disease progression in R/R multiple myeloma
Enzalutamide plus radium-223 extends survival in bone metastatic prostate cancer
ESMO 2025: Prostate highlights
HPK1 inhibitor NDI-101150 shows safety and antitumour activity in ccRCC
TAR-200 plus cetrelimab show encouraging outcomes for MIBC patients ineligible for standard cisplatin-based chemotherapy
CaboNivo shows sustained long-term benefits for survival and tumour progression as a 1L treatment of aRCC