Association between risk-reducing surgeries and survival in young BRCA carriers with breast cancer

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Published: 23 Dec 2024
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Dr Matteo Lambertini - San Martino Hospital, Genoa, Italy

Dr Matteo Lambertini talks to ecancer about a study he presented at the 2024 San Antonio Breast Cancer Symposium (SABCS) that investigated the association between risk-reducing mastectomies and survival outcomes in young women with breast cancer.

The BRCA BCY Collaboration (NCT03673306) was an international, multicenter trial that studied 5,290 young women with germline BRCA1 and/or BRCA2 mutations. The women were diagnosed with stage 1-3 invasive breast cancer at a median age of 35.

The study's results are set to help inform decisions about risk-reducing mastectomies and survival outcomes for young women with breast cancer.