Whole body-MRI and fluorine 18 fluorodeoxyglucose PET/CT shows promising diagnostic accuracy in multiple myeloma patients

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Published: 25 Jun 2024
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Dr Claudio Cerchione - IRCCS, Meldola, Italy

Dr Claudio Cerchione talks to ecancer about his study at EHA 2024.

His study evaluates the effectiveness of whole-body MRI (WB-MRI) and FDG PET/CT in detecting bone marrow infiltration in multiple myeloma patients.

Among 137 patients, WB-MRI showed higher sensitivity (94%) and specificity (98%) compared to PET/CT (81% and 94%), and influenced treatment decisions in 36% of cases compared to 31% for PET/CT.

The findings highlight the complementary role of both imaging techniques, with WB-MRI being particularly adept at identifying diffuse and micronodular patterns of bone marrow infiltration.