Low-dose olanzapine after highly emetogenic chemotherapy can be the new standard of care for solid tumours

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Published: 7 Dec 2023
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Dr Jyoti Bajpai - Tata Memorial Centre, Mumbai, India

Dr Jyoti Bajpai speaks to ecancer about her open-label phase III OLAnzaPiNE trial evaluating low-dose compared to standard-dose olanzapine with triple antiemetic therapy for prevention of highly emetogenic chemotherapy-induced nausea and vomiting in solid tumours.

Dr Bajpai initially talks about the objective and the design of the trial.

The study found that low-dose olanzapine is non-inferior to standard dose in anti-emetic efficacy and results in lower daytime somnolence among patients receiving highly emetogenic chemotherapy and could be a standard of care.