Key insights from lung cancer research at ASCO 2025
Dr Matthew Krebs (The Christie NHS Foundation Trust, Manchester, UK), Dr Antonio Passaro (European Institute of Oncology, Milan, Italy), Dr Enriqueta Felip (Vall d'Hebron University Hospital, Barcelona, Spain) and Prof Pascale Tomasini (Aix-Marseille University, Marseille, France) discuss the latest updates in EGFR mutated NSCLC from ESMO and WCLC 2024.
This expert discussion provides clinicians with an invaluable understanding of the current landscape of the treatment of lung cancer. The panellists cover various related studies from both these conferences.
The discussion is divided into the following sections:
| Latest updates on patients with common EGFR mutations | |
| Updates on EGFR Exon 20 insertion | |
| Take home messages |
Key insights from lung cancer research at ASCO 2025
ELCC 2025: Latest in EGFR positive NSCLC
ASCO 2024: Lung cancer highlights
ELCC 2024: Latest in EGFR mutant lung cancer; exon 20 mutation focus
ESMO 2023: Latest in EGFR Ex20ins advanced NSCLC
Pegargiminase-pemetrexed-platinum triplet therapy prolongs survival in non-epithelioid pleural mesothelioma
Amivantamab shows robust efficacy in post-platinum therapy patients with EGFR Ex20ins NSCLC
Four chemo cycles given with durvalumab and tremelimumab optimise response and tumour shrinkage in patients with mNSCLC
LUMINANCE: Results support use of durvalumab and platinum-etoposide for extensive stage SCLC