Prof Arthur Sun Myint speaks to ecancer as part of ASCO GI 2022 about the OPERA study which looked at the role of radiation dose escalation using Contact X-ray brachytherapy (CXB) in order to avoid surgery in rectal cancer.

He explains that patients were randomised between two arms: Arm A (standard of care with EBRT boost) and Arm B (experimental with CXB boost).

Prof Myint reports that surgical treatment is feasible and failures can still be salvaged with chances of survival not compromised.