ecancermedicalscience

Case Report

Use of PEG-asparaginase in a case of Hepatosplenic γδ T-cell lymphoma with long-term remission after stem cell transplantation

20 Sep 2018
Kai Sun, Cesar Gentille Sanchez, Sai Ravi Pingali, Swaminathan Iyer

Hepatosplenic γδ T-cell lymphoma (HSTCL) is a rare aggressive peripheral T-cell lymphoma. Prognosis is usually poor with a median survival between 8 and 16 months after traditional chemotherapy. Stem cell transplantation (SCT) is promising and with a more intense induction regimen, has yielded positive results. We report the use of pegylated-asparaginase (PEG-asparaginase) along with a conventional anthracycline-containing regimen in a 51-year-old male who was diagnosed with HSTCL, achieved a complete remission, and subsequently underwent peripheral blood SCT and remained in remission at the time of this case report.

Article metrics: 389 views
220
169

Related Articles

Fausto Maffini, Daniele Lorenzini, Daniela Lepanto, Elvio De Fiori, Caterina Fumagalli, Alessandra Rappa, Marta Tagliabue, Massimo Barberis
Kai Sun, Ryan J Reynolds, Tiffany G Sheu, Jessica A Tomsula, Lara Colton, Lawrence Rice
Ethan A Burns, Amna Ahmed, Anusha Sunkara, Usman Khan, Roozbeh Sharif, Maen Abdelrahim, Michael Reardon, Barry Trachtenberg
Marta Canesi, Chiara Broggi, Kizhan Fazil, Mardin Jafr, Laura Russo, Valentina Panzetti, Gloria Ciabatti, Giulia De Riso, Andrea Mastria, Hiwa Sadiq Sidiq
Liliana Castro Oliveira, Carlos Fardilha, Manuel Louro, Carlos Pinheiro, Abílio Sousa, Herlander Marques, Paulo Costa