ecancermedicalscience

Case Report

Malignant extra-adrenal pelvic paraganglioma in a paediatric patient

23 Aug 2017
Gabriel Cao, Julian Mendez, Daniel Navacchia

The extra-adrenal paraganglioma is a neoplasm originating in regional structures, uncommon in paediatrics. We report on a case of a 13-year-old patient who began with severe arterial hypertension, tachycardia, dilated cardiomyopathy and elevated levels of catecholamines in the blood and urine. The presence of a retrovesical pelvic mass in contact with the right vaginal dome was determined by imaging studies. A diagnosis of malignant extra-adrenal pelvic paraganglioma with lymph node metastases was reached through biopsy and the surgical resection of subsequent local recurrences. Paragangliomas are usually located in the paravertebral zones from the base of the skull to the retroperitoneum and are benign in 90% of cases. This kind of neoplasia is uncommon in paediatrics, especially those located in the pelvis. In cases of masses of a gynaecological origin, a differential diagnosis should be considered, and a histological and immunohistochemical study is essential in certifying the diagnosis.

Related Articles

Adu Bukola Gift, Michael Joseph Otorkpa, Oluwatobi O. Olayode, Ebubechukwu David Joseph, Ademola Abdulhakeem, Efuetlateh John Paul Nchonganyi, Feziechi Chikelundu Anele, Akolade Akeem Habib, Fodop Samuel Ghislain Junior, Oluwanifemi O. Akintoye, Omoregbee Benjamin
Dario Alvaro Rueda, Cecilia Schweitzer, Di Nisio Lorena, María Laura Piccoletti, Nicolas Torressi, Víctor Acevedo, Silvia Ferrandini
Rima Saad Rassam, Ryan R Lion, Siham Cherkaoui, Laila Hessissen, Ximena Garcia-Quintero, Lama Sayegh Najjar, Dolly Noun, Janane Hanna, Rana Yamout, Shahzadi Resham, Khaled Al Habaiba, Anwar Al-Nassan, Joe El-Khoury, Spandana Rayala, Qutaibah Alotaibi, Nahla Gafer, Giuseppe Troisi, Julia Downing, Suheir Rasul, Sima Jeha, Monnie Abraham, Michael J McNeil