ecancermedicalscience

Case Report

Primary pulmonary lymphoma in Peru

15 Jun 2023
Elily Dianet Apumayta Requena, Danery Valdez Ocrospoma, Jhonatanael Salvador Ruiz, Alberto De la Guerra Pancorvo, Edgar Amorin Kajatt

Objective: To describe the clinical features, imaging, pathology and management of patients with primary pulmonary lymphoma (PPL).

Methodology: This is a case series study involving a retrospective analysis of 24 patients diagnosed with PPL between the years 2000–2019 at Instituto Nacional de Enfermedades Neoplásicas in Lima, Perú.

Results: 73.9% of patients were male. Cough (78.3%) and weight loss (56.5%) were the most frequent clinical features. Dyspnoea and elevated values of DHL and B2 microglobulin were frequently altered in advanced stages. Diffuse large B cell lymphoma (DLBCL) represented 47.8% of the cases and the most common radiologic alterations were a mass (60%) and consolidation with air bronchogram (60%). The most utilised treatment was chemotherapy alone (60%). Three patients received only surgery. Median survival was 30 months. Five overall survival was 45%, and up to 60% in the case of mucosa-associated lymphoid tissue lymphoma.

Conclusion: PPL is infrequent. Clinical features are unspecific and the principal finding is a mass, nodule or consolidation with air bronchogram. Definitive diagnosis needs biopsy and immunohistochemistry. There is no standard treatment, it depends on histology type and stage.

Related Articles

Francisca Quintanilla, Álvaro Torres, Monserrat Villar, Catalina Muñoz, José Lizama, Bárbara Mena
Carla Climent, Sandra Soriano, Natalia Lopez, Julia Giner, Mari Carmen Blazquez, Ruben Carrera, Marina Sierra, Pablo Cobo, Monica Fragio, Mireia Busquets, Ona Cano I Cano, Alicia Carrasco, Miguel Ángel Seguí, Laia Vila
Ranti Ghosh, Debarshi Lahiri, Debjit Ghosh, Kushal Sen, Debanjan Chakraborty, Tapas Maji, Suparna Mazumder, Ranajit Mandal, Arit Bhattacharjee, Jayanta Chakrabarti
Shubham Dokania, Ajay K Choubey, Shashank Tiwari, Prasenjit Nath, Jhansi Pattanaik, Sambit S Nanda, Ashutosh Mukherji, Satyajit Pradhan