ecancermedicalscience

Case Report

Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome

17 Nov 2022
María Fernanda Toro-Wills, Angelina Álvarez-Londoño, Abraham Hernández-Blanquisett, Fernando Salas Marquez, María Cristina Martínez-Ávila

Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis can only be made based on histological examination and immunohistochemistry. To date, there aren’t standardised treatment protocols for its management. We report a case of a 73-year-old patient who presented postmenopausal abnormal uterine bleeding and was diagnosed with ECS. A non-conventional treatment approach was conducted with favourable oncological outcomes.

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