ecancermedicalscience

Short Communication

Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population

17 Feb 2022
Devyani Gholap, Sharayu Mhatre, Pankaj Chaturvedi, Sudhir Nair, Tarik Gheit, Massimo Tommasino, Rajesh Dikshit

Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in the western region of India. Type-specific multiplex genotyping assay was conducted at the Centre for Cancer Epidemiology, Tata Memorial Centre, to determine the prevalence of HPV subtypes. The HPV prevalence was observed to be 28.43%, 41.67%, 38.89% and 15.79% in the oral cavity, oropharynx, hypopharynx and larynx tumour tissues, respectively. The HPV 16 genotype was most common in all HNC tumour tissues (30.29%), followed by HPV 58 (0.57%).

Related Articles

Atul Budkh, Sonali Bagal, Deepak Gupta, Sharyu Mhamane, Ravikant Singh, Burhanuddin Qayyumi, Abha Rani Sinha, Sanjay Kumar Singh, Satyajit Pradhan, Pankaj Chaturvedi, Rajendra Badwe, Sudeep Gupta
Calvin R Flynn, Roselle de Guzman, Olubukola Ayodele, Joan H Schiller, Katie Lichter, E Shelley Hwang, Lisa Fox, Gustavo Gosling, Claire Hopkins, Ken Rogan, Eduardo Cazap, Seamus O’Reilly
Camilla Engelsmann, Gitte Wooler, Vladimira Horvat, Shailesh Balasaheb Kolekar
Simran Malik, Sudipta Mukherjee, Pralay Shankar Ghosh, Santanu Bagchi, Gaurav Goel, Soumyadip Chatterji, Saugata Sen, Debashree Guha Adhya, Sangeeta Das Bhattacharya, Sanjay Bhattacharya
Aleyamma Mathew, Preethi Sara George, Kondalli Lakshminarayana Sudarshan, Thilagavathi Ramamoorthy, Sreekumar Ananthakrishna, Elizabeth Mathew Iype, Anita Nath