ecancermedicalscience

Case Report

The recurrence of the melanotic neuroectodermal tumour of infancy: an unusual presentation of a rare tumour

26 May 2020
Antonio Augusto Claudio Pereira, Mayara Maria de Jesus Rozante, Rafael Bauer Doveinis, Carmine Porcelli Salvarani, Tania Hissa Anegawa, Paola da Costa Souza, Daniel J Brat, Alessandra Cristina de Oliveira Borges

The melanotic neuroectodermal tumour of infancy (MNTI), also known as melanotic progonoma, is a rare neoplasm derived from neural crest cells. Although it is fundamentally benign, the tumour may present a locally aggressive behaviour, characterised by a rapid progression and a destructive invasion of adjacent structures, hence causing deformities. Unfortunately, perhaps due to the low incidence of this type of tumour, the published cases in the literature do not characterise the factors that imply the malignant or recurrent behaviour of the disease, nor the therapy to conduct these cases. Here, we report a rare case of a recurrent benign MNTI, approached unusually with a favourable outcome.

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