ecancermedicalscience

Special Issue

Fertility preservation in patients with BRCA mutation

6 May 2020
Suleiman Ghunaim, Ghina Ghazeeri, Dalia Khalife, Hatem A Azim Jr

Evidence suggests a likely negative impact of deleterious BRCA mutations on female fertility. Hence, different studies have aimed to address the reproductive potential and performance of fertility preservation strategies in BRCA-mutated breast cancer patients with a prime focus on their safety and efficacy. However, several uncertainties exist in many domains of this field. The aim of the current paper is to overview the reproductive potential and fertility preservation options in breast and ovarian cancer patients harbouring a BRCA mutation. We also discuss pre-implantation genetic testing in an attempt to help physicians during oncofertility counselling of these patients.

Related Articles

Josephine Nsaful, Florence Dedey, Kirstyn E Brownson, Ruth Y Laryea, Nathaniel Coleman, John Tetteh, Mohammed Albezel Sheriff, Joe-Nat Clegg-Lamptey, Benedict N L Calys-Tagoe
Joseph Daniels, Onesmus Iinekela Amunyela, Andrew Yaw Nyantakyi, Edwina Ayaaba Ayabilah, Judith Naa Odey Tackie, Kofi Adesi Kyei
Kamran Saeed, Kaynat Siddiqui, Hafiza Fatima Aziz, Fatima Shaukat, Shazia Kadri, Aneeta Ghulam Muhammad, Aneela Darbar, Tariq Mahmood
Akhil Kapoor, Anuj Gupta, Bipinesh Sansar, Pooja Gupta, Bal Krishna Mishra, Arpita Singh, Arvind Upadhyay, Amit Kumar, Mayank Tripathi, Zachariah Chowdhury, Shashikant Patne, Ipsita Dhal, Neha Singh, Shreya Shukla, Satyendra Narayan Singh, Lincoln Pujari, Prashanth Giridhar, Ankita Rungta Kapoor, Yash Jain, Manikandan Venkatachalam, Somnath Dey, Kunal Ranjan Vinayak