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NCRI 2010 /
Chemoradiotherapy for bladder cancer

7th - 10th Nov 2010

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Published: 14.01.11
Views: 6070

Prof Nick James - Queen Elizabeth Hospital and University of Birmingham, UK

Prof Nick James explains the results of his study into chemoradiotherapy for patients with bladder cancer. Radiotherapy alone is associated with a high recurrence rate, but when successful it is superior to surgery. This study demonstrated that combining fluorouracil and mitomycin C as radiosensitisers reduces locoregional recurrence by 33%. The reduction in recurrence rate was primarily in invasive recurrences rather than less serious superficial recurrences and the addition of the radiosensitisers only produced a minimal increase in side effects. Prof James speaks about the background to this study, discusses how the fluorouracil mitomycin C radiosensitiser combination was chosen and briefly outlines the second part of the trial which examined how a reduction in radiotherapy dose affected toxicity.

Previous conferences: highlights

Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation