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Abstract | Full HTML Article | PDF | Portuguese ecancer 9 593 / https://doi.org/10.3332/ecancer.2015.593

Review

Infracentimetric HER-2 positive breast tumours—review of the literature

Breast cancer is the most common malignant neoplasm in the world among women. As a result of the dissemination of population screening programmes, about half of non-metastatic breast cancers are now diagnosed at stage I. 10–15% of T1abN0 tumours over-express human epidermal growth factor (HER-2). These tumours have a globally excellent prognosis, however, treatment with chemotherapy and/or targeted therapy may further improve outcomes in selected cases. In this article, we will review studies with information on prognosis and benefit of adjuvant therapy for T1abN0 HER-2 breast cancer.

Keywords: Breast cancer, infracentimetric, HER-2 positive breast cancer

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European Cancer Organisation European Institute of Oncology

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