Our website uses cookies to improve your on-site experience. By using the website, cookies are being used as described in our Policy Document
Warning: To log in you will need to enable cookies and reload the page (Policy Document)
My ePortfolio Register   
 

Abstract | Full HTML Article | PDF ecancer 9 499 / https://doi.org/10.3332/ecancer.2015.499

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Keywords: angiosarcoma, metronomic chemotherapy, drug repositioning, palliative treatment, beta-blockers, propranolol, celecoxib, etoposide, cyclophosphamide

Loading Article Metrics ... Please wait

Related articles

Review: Non-gastrointestinal stromal tumours soft tissue sarcomas: an update

Abstract | Full Article | PDF Published: 13 Aug 2019 / https://doi.org/10.3332/ecancer.2019.958

Clinical Study: Early toxicity and treatment outcomes of extended field-intensity modulated radiotherapy for cervical cancer patients with para-aortic nodal metastasis

Abstract | Full Article | PDF Published: 06 Aug 2019 / https://doi.org/10.3332/ecancer.2019.957

Research: Effect of radiation dose to the periventricular zone and subventricular zone on survival in anaplastic gliomas

Abstract | Full Article | PDF Published: 31 Jul 2019 / https://doi.org/10.3332/ecancer.2019.956

Research: Nurse-led renal cancer follow-up is safe and associated with high patient satisfaction—an audit from the East of England

Abstract | Full Article | PDF Published: 30 Jul 2019 / https://doi.org/10.3332/ecancer.2019.955

Case Report: Synchronous peritoneal carcinomatosis from a buccal squamous cell carcinoma: a case report focusing on possible metastatic mechanisms and novel therapeutic modalities

Abstract | Full Article | PDF Published: 29 Jul 2019 / https://doi.org/10.3332/ecancer.2019.954



Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation