Neoadjuvant PD-1 blockade enables organ preservation in early dMMR tumours without surgery
Dr Zev Wainberg speaks to ecancer about the phase Ib study of the anti-TIGIT antibody tiragolumab in combination with atezolizumab in patients with metastatic oesophageal cancer. Initially, he explains the background of the study.
He then, discusses the methodology and results of this study.
Dr Wainberg concludes, saying that tiragolumab combined with atezolizumab was well-tolerated with an acceptable safety profile, and showed preliminary anti-tumour activity in heavily pretreated patients with metastatic oesophageal cancers not previously treated with cancer immunotherapy.
Neoadjuvant PD-1 blockade enables organ preservation in early dMMR tumours without surgery
Comment: Trial updates from GALAXIES Lung-201 and RELATIVITY-104 in NSCLC
Understanding the use of PARPi combinations to treat patients with mCRPC
ESMO 2024: Optimising the personalisation of prostate cancer treatment
Durvalumab, gemcitabine and cisplatin continue to show clinically meaningful long-term survival in biliary tract cancer patients
Hormonal receptor positive breast cancer adjuvant and metastatic indications
Uncommon genetic aberrations NTRK, RET, NRG
ASCO 2024: Lung cancer highlights
Immunotherapy significantly increases the number of patients free from bowel cancer