Gene expression test guided therapy in ER+/HER2- early breast cancer allows safe chemotherapy omission

Tarlatamab in SCLC shows consistent effect and low immune toxicity across age groups

Adjuvant avelumab reduces relapse risk in stage III Merkel cell carcinoma

Fedratinib improves spleen and symptom responses with promising survival outcomes in MDS/MPN and CNL

177Lu-rosopatamab plus standard of care shows manageable safety and favourable tumour targeting in mCRPC

Darovasertib plus crizotinib improves outcomes in HLA-A2–negative metastatic uveal melanoma

Early-onset gastrointestinal cancers show more advanced disease and wider racial survival gaps

Xaluritamig plus abiraterone shows promising anti-tumour activity with manageable safety in chemotherapy-naïve mCRPC

Tarlatamab improves brain metastases control and survival compared to chemo in SCLC

Mezigdomide plus carfilzomib and dexamethasone delays disease progression in R/R multiple myeloma

Aspirin use linked to improved survival in endometrial cancer

Daraxonrasib nearly doubles survival in previously treated metastatic pancreatic cancer