Daraxonrasib nearly doubles survival in previously treated metastatic pancreatic cancer

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Published: 31 May 2026
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Dr Brian Wolpin - Dana-Farber Cancer Institute, Boston, USA

Dr Brian Wolpin talks to ecancer at ASCO 2026 about results from the phase 3 RASolute 302 trial evaluating daraxonrasib as second-line treatment for metastatic pancreatic ductal adenocarcinoma.

The RAS(ON) multi-selective inhibitor nearly doubled overall survival and improved progression-free survival and response rates compared with chemotherapy, with fewer serious side effects.

Dr Wolpin notes that daraxonrasib has potential as anew standard of care in the second-line setting for metastatic pancreatic cancer.

Read the news story here.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.