Epigenetic expression in T cell leukaemia

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Published: 24 May 2019
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Dr Sinisa Dovat - Penn State Cancer Institute, Hershey, USA

Dr Sinisa Dovat talks to ecancer at the European School of Haematology (ESH) meeting: International Conference on Acute Lymphoblastic Leukaemia about the epigenetic regulation in T-cell leukaemia.

He explains how the function of the tumour suppressor, IKZF1/Ikarus, its role in leukaemia and how these can be a target for therapy.

Dr Dovat discusses the next steps for this research, which include examining epigenetic expression using human B cells and T cells and a phase I trial for these haematologic malignancies.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.