An integrated view of the role of the B cell antigen receptor in lymphoma cell fitness

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Published: 3 Dec 2018
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Dr Stefano Casola - Institute of Molecular Oncology Foundation, Milan, Italy

Dr Stefano Casola speaks to ecancer at ASH 2018 about the role of the B cell antigen receptor in metabolism in malignant cells.

He explains that it was discovered through animal models that when the B cell receptor is lost the cells learn to adapt and use other ways to survive.

Dr Casola outlines that there has been a large scale screening for FDA approved drugs that can target and kill these cells meaning if such a drug is found clinical trials can begin immediately.