Latest in hepatocellular carcinoma treatments

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Published: 4 Jun 2016
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Dr Ghassan Abou-Alfa - Memorial Sloan Kettering Cancer Center, New York, USA

Dr Abou-Alfa speaks with ecancertv at ASCO 2016 about two trials treating hepatocellular carcinoma; a combination therapy of sorafenib and doxorubicin, and ADI-peg20.

Dr Abou-Alfa summarises the background of target determination in both trials, focussing on arginine-citruline synthesis in HCC tumour microenvironment and the history of doxorubicin as a single or combination therapy.

In both trials, the therapies in question did not improve overall survival.

With these results in mind, Dr Abou-alfa discusses future avenues for research.

For more on novel HCC treatments, click here.