Prof Michael Baumann from the Medical Faculty Carl Gustav Carus, University of Technology, Dresden, Germany, and new head of ECCO, talking at ECCO 15 - ESMO 34, Berlin, Sept 2009. What's driving radiation oncologists at the moment. Changing practice to take into account genetic information on resistance to radiation. Combining genetic information with imaging. Normal tissue reactions. Manipulating hypoxia to the advantage of radiotherapy, How familial cancer genes affect therapy.