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Targeting death receptors in chemo-resistant cancer cells

2009 ASCO Annual Meeting

29 May - 2 Jun 2009

Published: 3 Jul 2009

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Prof Patrick Johnston - Queen's University Belfast, UK

Prof Patrick Johnston, Centre for Cancer Research & Cell Biology, Queen's University Belfast, discusses his work targeting the BCL2 protein family and other inhibitors of cell apoptosis in order to prevent cancer cells resisting chemotherapy. Agents such as Obatoclax, ABT243 and proteins such as c-FLIP. For cancers such as lung, prostate, breast and ovarian.

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