Poor prognosis on small, HER2 positive tumours

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Published: 9 Mar 2009
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Dr Ana M. Gonzalez-Angula - Department of Breast Medical Oncology, Department of Systems Biology at the University of Texas M.D. Anderson Cancer Center
Although current guidelines call for no further therapy after surgery on breast tumours one centimeter or smaller, a new study suggests that if these tumors are HER2 positive patients have an increased risk for relapse. In the largest study of its kind to date (n=1,315, including a validation set), researchers found that the five-year recurrence rate was 23 percent among patients with small HER2-positive tumours, compared with eight percent in other tumour types. Speaking at San Antonio Breast Cancer symposium 2008.