Advancements in gastrointestinal cancer treatments at ASCO 2025

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Published: 31 Jul 2025
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Dr Jesus Fabregas - Memorial Cancer Institute, Miami, USA

Dr Fabregas explains how ASCO 2025 showcased the major advancements in gastrointestinal cancer treatments.

The MATTERHORN trial demonstrates that adding durvalumab immunotherapy to standard care for gastric cancer enhances event-free survival and pathologic response rates.

The ATOMIC trial reports a 50% increase in disease-free survival for colorectal cancer patients treated with atezolizumab and chemotherapy.

The BREAKWATER trial indicates improved overall survival for patients with BRAF-mutated colorectal cancer (CRC), with future research focusing on immunotherapy to reduce treatment-related toxicities.