Dr Jay Detsky speaks to ecancer about results from the UNITED single-arm phase II trial. This trial investigated MR-Linac on-line weekly adaptive radiotherapy for high-grade glioma (HGG).

A new treatment paradigm for glioblastoma is being tested using adaptive radiation guided by daily MR imaging.

This study includes two cohorts receiving different durations of radiation and focuses on reducing the risk of marginal failure.

Results show a significant decrease in failure rates compared to historical data, with no negative impact on survival rates.

These findings may pave the way for more personalised radiation therapies in the future.