Antiangiogenic therapies for non-small cell lung cancer

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Published: 24 Nov 2011
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Prof Roman Perez-Soler - Montefiore Medical Center, New York, USA
The introduction of bevacizumab with carboplatin taxol therapy for the treatment of non-small cell lung cancer has been highly successful and has increased survival in these patients. Although studies evaluating other anti-angiogenesis therapies that target the same pathway have been unsuccessful, the reasons for this are unclear. Prof Roman Perez-Soler outlines the potential for new anti-angiogenesis drugs which target alternative pathways. It is hoped that these agents can be used to successfully treat patients who experience unacceptable levels of adverse effects from bevacizumab.