Dr Mary McCormack speaks to ecancer about the GCIG INTERLACE trial. This is a randomised phase III trial of induction chemotherapy followed by chemoradiation compared with chemoradiation alone in locally advanced cervical cancer.
This trial investigated whether short-course weekly induction chemotherapy delivered before standard chemoradiation improves both progression-free survival (PFS) and overall survival (OS).
The study found out that induction chemotherapy followed by CRT significantly improves progression-free survival and overall survival in locally advanced cervical cancer and should be considered as a new standard of care.