ecancermedicalscience

Research

Individual-level determinants of late-stage cervical cancer diagnosis and their implications for prevention and control

7 Oct 2025
Adeniyi K Akiseku, Taiwo O Adenuga, Olusoji E Jagun, Mutiu A Popoola, Adetola O Olatunji

Background: Cervical cancer remains a significant public health issue, particularly in low-income countries. It is the fourth most common cancer among women globally, with an estimated 570,000 new cases and 311,000 deaths in 2018.

Objective: This study aimed to examine the stages of cervical cancer at diagnosis and identify factors contributing to late-stage presentation among women in a tertiary care hospital in Nigeria.

Methods: A retrospective study analysed data from women diagnosed with cervical cancer between 2017 and 2021. Demographic, reproductive and clinical data were extracted from medical records.

Results: Of the 102 women who presented during the study period, only 57 (55.9%) had complete staging, clinical and demographic data; these complete cases were included to ensure data integrity. From this population, 73.7% were aged 50 years or older and 56.1% presented with late-stage disease. Additionally, anaemia (packed cell volume <30%) was present in 75.4% of women. Postcoital bleeding was reported in 35.1% of cases. Women with no formal education had higher odds of late-stage diagnosis odds ratios (OR: 4.40, 95% CI: 1.08–17.82). Postmenopausal women also had higher odds of late-stage diagnosis (OR: 4.46, 95% CI: 1.27–15.70).

Conclusion: A late-stage cervical cancer diagnosis is prevalent among women in Nigeria, particularly among those with lower educational levels and postmenopausal women. Targeted awareness programmes, expanded screening (including integration into well-woman/postmenopausal care) and improved healthcare infrastructure, including consistent documentation of screening history and human papillomavirus vaccination, are essential for reducing the burden of cervical cancer in this context.

Related Articles

Clara Pierini, Clara Mariano y Jelicich, Fabiola Bascuñán Acuña, María De San Martín, Aldana Casati, Cecilia Casullo, Marta Díaz Madero, Delfina Grennon Viel, Estefania Marzik, Gabriela Rodriguez, Victoria Viel Temperley
Ochomo Edwin Onyango, Philiph Tonui, Peter Itsura, Elkanah Omenge Orang'o, Kapten Muthoka, Sayo Loice, Benard Ochieng Samba, Barry Rosen, Patrick Loehrer, Susan Cu-Uvin
Abeir El-Mogassabi, Heithum Saleh Baiu, Nadin Omer Hassan, Enas Mohamed Salem, Lugien Elshakmak, Khalil A K Tamoos, Mohammed Zidan, Asma Rajab Ben Rashid, Ala Elhoudiri, Sama Elmehdawi, Dania Shareia
Marco Aurélio Bertúlio das Neves, Noemi Dreyer Galvão, Fernanda Cristina da Silva de Lima, Júlio Fernando Pinto Oliveria, Sancho Pedro Xavier, Ageo Mário Cândido da Silva
Raul Puente-Vallejo, Alex García-Gutiérrez, Sebastián Jara-Jimenez, Martina Natalia Mosquera-Ruiz, Wilmer Tarupi