Cancer cells recruit normal cells such as endothelial cells, immune cells, adipocytes and fibroblasts, to establish a reactive tumour microenvironment. Researchers are rapidly expanding our knowledge of how cancer and stromal cells communicate, via metabolic changes and inflammation, and establish a symbiotic relationship that supports malignant progression and suppresses anti-tumour immunity.

Throughout the meeting there will be an emphasis placed not only on the mechanisms underlying the metabolic crosstalk established between cancer cells and stromal cells, but also on the impact of context-specific metabolism on cancer development and progression, and on how to therapeutically target these metabolic processes in cancer.

This meeting will bring together diverse researchers from the fields of cancer metabolism and stromal cell biology, providing an opportunity to discuss recent developments and new areas of cross-fertilisation between those fields.

The Main Topics will include:

• Tumour microenvironment metabolic pathways and tumour progression
• Metabolism of circulating tumour cells and cancer stem cells
• Inflammation and cancer initiation
• Immune microenvironment and tumour progression
• Targeting metabolism for cancer therapy