Learning Objectives

Participants will acquire knowledge on:

• Molecular mechanisms of cancer for clinical evaluation
• Pathology versus molecular biology for cancer diagnosis and response to treatment : Specific role and value
• Molecular oncology tests
• The next generation technologies underlying molecular diagnostics today
• New trends in clinical trials

Main Topics
• Role of EGFR in different cancers
• HPV related malignancies ( priority for head and neck)
• Molecular analysis of archive tissues: Next generation technologies and molecular diagnostic laboratories, genomic screening and diagnostic
• Molecular mechanisms and signaling pathways as hallmarks of cancer
• Gene regulation including chromatin structure and remodeling, transcription, RNA processing and stability, and translation relevant to oncogenesis
• Role of characterized stem cells in tumor validation
• Cell death pathways (both apoptotic and non-apoptotic)
• Proteomics and functional genomics for clinical evaluation
• Scan pathology
• Implementation of virtual microscope slides in pathobiology of cancer
• Developing of molecular clinical trials – molecules in clinical development